PhD student

The Milner Centre for Evolution
Department of Biology & Biotechnology
University of Bath
Claverton Down
Bath, BA2 7AY
United Kingdom
Twitter: @Jess_Calland
E-mail: J.K.Calland@bath.ac.uk
Phone: +44 (0) 1225-383717

Professional profiles (14 publications; H-index: 6)
ORCiD | Google Scholar | ResearchGate

Curriculum
2017- : PhD student, The Milner Centre for Evolution (University of Bath)
2015-2016: MSc, Molecular Microbiology (University of Bath)
2010-2013: BSc, Tropical Disease Biology (University of Liverpool)

Research interests
My research interests involve studying the population genetics of bacterial species to gain a better understanding of their ability to diversify and occupy new hosts/niches and how this can alter over time. Campylobacter is the leading cause of foodborne gastroenteritis world-wide and the main source of infection in humans is associated with undercooked, contaminated chicken. Understanding the ecology and evolution of microbes is integral to implementing control strategies that limit infection. A core part of my PhD research has been to utilise genomics in order to design a vaccine for the control of Campylobacter infection in poultry.

Publications (* indicates joint authorship)
Mouftah SF*, Pascoe B*, Calland JK, Mourkas E, Tonkin N, Lefevré C, Deuker D, Smith S, Wickenden H, Hitchings MD, Sheppard SK, Elhadidy M (2021) Local accessory gene sharing drives lineage-specific acquisition of antimicrobial resistance in Egyptian Campylobacter spp. bioRxiv doi: TBC [Preprint]

Mourkas E, Yahara K, Bayliss SC, Calland JK, Johansson H, Mageiros L, Muñoz-Ramirez ZY, Futcher G, Méric G, Hitchings MD, Sandoval-Motta S, Torres J, Jolley KA, Maidem MCJ, Ellström P, Waldenström J, Pascoe B* & Sheppard SK* (2021) Host ecology regulates interspecies recombination in bacteria of the genus Campylobacter. bioRxiv doi: 10.1101/2021.08.24.457495 [Preprint] Supplementary material [figshare] Twitter [thread]

Kittiwan N, Calland JK, Mourkas E, Hitchings MD, Murray S, Tadee Ph, Tadee Pa, Duangsonk K, Méric G, Sheppard SK, Patchanee P*, Pascoe B* (2021) Non-serotype 2 isolates from healthy pigs are a potential zoonotic reservoir of Streptococcus suis genetic diversity and antimicrobial resistance. bioRxiv doi: 10.1101/2021.06.17.447897 [Preprint]; Sequence data [NCBI]; Supplementary material [figshare]; Genealogy [microreact]; Twitter [thread]

Taylor AJ*, Méric G*, Yahara K, Pascoe B, Mageiros L, Mourkas E, Calland JK, Puranen S, Hitchings MD, Bayliss SC, Jolley KA, Kobras CM, Williams NJ, van Vliet AHM, Parkhill J, Maiden MCJ, Corander J, Falush D, Didelot X, Kelly DJ*, Sheppard SK* (2021) Cross-species evolutionary rewiring in the enteric bacterium Campylobacter. bioRxiv doi: 10.1101/2021.03.15.435406 [Preprint]; Sequence data [1][2]; Supplementary material [figShare]; Twitter [thread]

Calland JK, Pascoe B, Bayliss SC, Mourkas E, Thorpe HA, Yahara K, Berthenet E, Hitchings MD, Feil EJ, Corander J, Blaser MJ, Falush D & Sheppard SK (2020) Quantifying bacterial evolution in the wild: a birthday problem for Campylobacter lineages. PLoS Genetics 17(9): e1009829 [Publisher]; bioRxiv doi: 10.1101/2020.12.02.407999 [Preprint]; Sequence data [NCBI]; Supplementary material [figShare]; Twitter [thread]

Peters S*, Pascoe B*, Wu Z, Bayliss SC, Zeng X, Edogawa S, Edwinson A, Veerabadhran-Gurunathan S, Jawahir S, Calland JK, Mourkas E, Patel R, Wiens T, Decur M, Boxrud D, Smith K, Parker CT, Farrugia G, Zhang Q, Sheppard SK**, Grover M** (2021) Campylobacter jejuni genotypes associated with post infection irritable bowel syndrome in humans. Communications Biology 4: 1015 [Publisher]; Sequence data [SRA]; Supplementary material [figshare]; Genealogy [microreact]; Twitter [@benizao][@mgrover_gi]; Reddit [r/IBSresearch]

Mageiros L, Méric G, Bayliss SC, Pensar J, Pascoe B, Mourkas E, Calland JK, Yahara K, Murray S, Wilkinson TS, Williams LK, Hitchings MD, Kemmett K, Feil EJ, Jolley KA, Williams NJ, Corander J, Sheppard SK. (2020) Genome evolution and emergence of pathogenicity in Avian Escherichia coli. Nature Communications (accepted); Sequence data [NCBI]; Supplementary material [figShare]

Mouftah S*, Cobo-Diaz JF*, Álvarez-Ordóñez A, Mousa A, Calland JK, Pascoe B, Sheppard SK & Elhadidy M. (2020) Stress-resistance is associated with multi‐host transmission and enhanced biofilm formation among hyper-aerotolerant generalist Campylobacter jejuni. Food Microbiology (In press) doi: 10.1016/j.fm.2020.103706 [Publisher] Sequence data [SRA]

Pascoe B, Schiaffino F, Murray S, Méric G, Bayliss SC, Hitchings MD, Mourkas E, Calland JK, Burga R, Peñataro-Yori P, Jolley KA, Cooper KK, Parker CT, Paredes-Olortegui M, Kosek M & Sheppard SK. (2020) Genomic epidemiology of Campylobacter jejuni associated with asymptomatic pediatric infection in the Peruvian Amazon. PLOS NTD 14(8):e0008533; doi: 10.1371/journal.pntd.0008533 [Publisher]. medRxiv doi: 10.1101/2020.04.26.20075689 [Publisher], sequence data [SRA], Supplementary material [figShare], genealogies [1][2].

Mourkas E, Taylor AJ, Méric G, Bayliss SC, Pascoe B, Mageiros L, Calland JK, Hitchings MD, Ridley A, Vidal A, Forbes KJ, Strachan NJC, Parker CT, Parkhill J, Jolley KA, Cody AJ, Maiden MCJ, Kelly DJ*, Sheppard SK* (2020) Agricultural intensification and the evolution of host specialism in the enteric pathogen Campylobacter jejuni. PNAS 117 (20) 11018-11028; doi: 10.1073/pnas.1917168117 [Publisher]; Sequence data [SRA]; Supplementary material [figShare]

Patchanee P, Tanamai P, Tadee Ph, Hitchings MD, Calland JK, Sheppard SK, Meunsene D, Pascoe B* & Tadee Pa* (2020) Whole-genome characterisation of multidrug resistant monophasic variants of Salmonella Typhimurium from pig production in Thailand. PeerJ 8:e9700; doi:10.7717/peerj.9700 [Publisher]; Sequence data [SRA]; Supplementary material [FigShare]; Genealogy [microreact]

Banaszkiewicz S, Calland JK, Mourkas E, Sheppard SK, Pascoe B & Bania J. (2019) Genetic diversity of composite enterotoxigenic Staphylococcus epidermidis pathogenicity islands. Genome Biology and Evolution 11 (12) 3498–3509; doi.org/10.1093/gbe/evz259 [Publisher] Supplementary material [Figshare] Genomes [StaphDb] Genealogy [Microreact]

Mourkas E*, Florez-Cuadrado D*, Pascoe B, Calland JK, Bayliss SC, Mageiros L, Méric G, Hitchings MD, Quesada A, Porrero C, Ugarte-Ruiz M, Gutierrez-Fernandez J, Dominguez L, Sheppard SK. (2019) Gene pool transmission of multidrug resistance among Campylobacter from livestock, sewage and human disease. Environmental Microbiology 21 (12) 4597-4613; doi:10.1111/1462-2920.14760 [Publisher] Sequence data [SRA]

Pascoe B*, Williams LK*, Calland JK, Méric, G, Hitchings MD, Dyer M, Ryder J, Shaw S, Lopes BS, Chintoan-Uta C, Allan E, Vidal A, Fearnley C, Everest P, Pachebat JA, Cogan TA, Stevens MP, Humphrey TJ, Wilkinson TS, Cody AJ, Colles FM, Jolley KA, Maiden MCJ, Strachan N, Pearson BM, Linton D, Wren BW, Parkhill J, Kelly DJ, van Vliet AHM, Forbes KJ, Sheppard SK. (2019) Domestication of Campylobacter jejuni NCTC 11168. Microbial Genomics 10.1099/mgen.0.000279 [Publisher]; bioRxiv doi: 10.1101/591701 [Publisher] Supplementary data [Figshare] Genealogy [Microreact] Sequence data [SRA] European nucleotide archive [ENA]